North American Pharmacist Licensure Examination (NAPLEX) - Test Prep Actual Exam Questions
Last updated on May 01, 2026
Which of the following statements is true regarding Drug-receptor bonds?
Covalent bonds of drugs with receptors are strong and mostly reversible
Covalent bonding is much more common than electrostatic bonding in drug-receptor interactions
Electrostatic bonds are stronger than covalent bonds
Hydrophobic bonds are weak bonds and they are important in the interactions of highly water soluble drugs with the lipids of cell membranes
Bond formation of between the acetyl group of aspirin and cyclo-oxygenase enzyme is a covalent bond
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A 7-year-old boy has been suffering from influenza and had been given a drug by his father to decrease his high fever. A few hours later, his father brought him to the emergency room in a comatose state with a papulovesicular rash all over the body, moderate hepatomegaly, and asterixis. Laboratory studies reveal elevated levels of blood ammonia, AST, ALT, and PT. CT scan findings are suggestive for generalized cerebral edema. The drug the father gave his son is most likely which of the following drugs?
Aspirin
Acetaminophen
Indomethacin
Mefenamic acid
Diclofenac
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Which of the following are non-pharmacological measure that may control symptoms of gastroesophageal reflux disease?
Remain upright after a meal
Increase fat intake to reduce gastric emptying time Reduce intake of food or beverage that may reduce
lower esophageal sphincter tone
Wear tight fitted cloths to increase intra-abdominal pressure.
Discontinue nicotine use in patients that uses tobacco product.
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Which of the following side effects should LT be made aware of while on Divalproex Sodium?
Weight gain
Oligomenorrhea
Alopecia
Gynecomastia
Gingival hyperplasia
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If you mix 30 gm 5% lidocaine cream and 90gm of 0.5% hydrocortisone cream, what percent of lidocaine and hydrocortisone do you have as the end product?
Lidocaine/Hydrocortisone 2%/1.25%
Lidocaine/Hydrocortisone 0.375%/0.15%
Lidocaine/Hydrocortisone 1.25 %/ 0.15%
Lidocaine/Hydrocortisone 2% /0.25%
Lidocaine/Hydrocortisone 1.25% /0.375%
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